This paper presents research conducted to examine the potential of using longitudinal vibration techniques to evaluate the modulus of elasticity and strength of cross-laminated timber (CLT). Thirty-nine CLT panels were manufactured from southern pine dimension lumber in accordance with accepted manufacturing standards. Nominal 2 by 8 in. southern pine lumber specimens were used for the three-ply panels. A 10-ft-long specimen, having a 4.125- by 18-in. cross-section, was obtained from each panel. Weight and dimensions were determined for each specimen, and longitudinal vibration nondestructive evaluation techniques were used to determine frequency of oscillation and energy loss characteristics of the specimens. The dynamic modulus of elasticity was then determined. Each specimen was then tested to failure in a flatwise (third point) bending mode. Flatwise bending modulus of elasticity and strength (modulus of rupture) were determined. Excellent correlative relationships were observed between dynamic and flatwise bending moduli. A strong positive relationship was observed between the dynamic modulus and flatwise bending strength. Nondestructive testing of CLT panels is recommended for quality control protocols.