Sustainability issues are driving the civil construction industry to adopt and study more environmentally friendly technologies as an alternative to traditional masonry/concrete construction. In this context, plantation wood especially stands out as a constituent of the cross-laminated timber (CLT) system, laminated wood glued in perpendicular layers forming a solid-wood structural panel. CLT panels are commonly connected by screws or nails, and several authors have investigated the behavior of these connections. Glass-fiber-reinforced polymer (GFRP) dowels have been used to connect wooden structures, and have presented excellent performance results; however, they have not yet been tested in CLT. Therefore, the objective of this study is to analyze the glass-fiber-reinforced polymer (GFRP)-doweled connections between CLT panels. The specimens were submitted to monotonic shear loading, following the test protocol described in EN 26891-1991. Two configurations of adjacent five-layer panels were tested: flat-butt connections with 45° dowels (x, y, and z axes), and half-lap connections with 90° dowels. The results were evaluated according to the mechanical connection properties of strength, stiffness, and ductility ratio. The results showed higher stiffness for butt-end connections. In terms of strength, the half-lap connections were stronger than the butt-end connections.