Timber-concrete composite slabs are more and more in use: the combination of timber and concrete combines the advantages of both materials and offer a valid solution for the increasing demand for sustainable construction. The connection between timber and concrete is the crucial element, yet its potential regarding material and time expenses is not exploited. This paper presents the novel connection system micro-notches, an interlocking concept between timber and concrete with indentations in the millimetre range. Micro-notches provide a continuous shear transfer without additional steel fasteners such as screws or dowels. The paper presents the development of the micro-notch concept in an extensive experimental program supplemented with analytical and numerical models, a calculation model, and practice-relevant guidelines. The results of the investigations show that micro-notches feature an approximately rigid composite action between timber and concrete and a sufficient shear strength for the use in office and residential buildings.