Wood preservation is an important issue for agricultural buildings with timber structure. This is among others due to their halfway opened construction, high level of moisture release from livestock breeding or storing goods. However, regarding the possibly high moisture content in the building structure and the potential threat caused by wood-destroying organisms, there is still a substantial need for research. The latest results of the research work carried out by Technical University of Munich, in cooperation with the Bavarian State Research Center for Agriculture, show that, for the most agricultural buildings built from spruce, no preventative chemical wood preservation is necessary to ensure a durable construction.