The goal of this project is to contribute to the development of design values for cross-laminated timber (CLT) diaphragms in the seismic load-resisting system for buildings. Monotonic and cyclic tests to determine strength and stiffness characteristics of 2.44 m (8 ft) long shear connections with common self-tapping screws were performed. Understanding and quantifying the behavior of these shear connections will aid in developing design provisions in the National Design Specification for Wood Construction and the International Building Code so structural engineers can use CLT more confidently in lateral force-resisting systems and extend the heights of wood buildings. Experimental strength-to-design strength ratios were in the range of 2.1 to 8.7. In the ASCE 41 acceptance criteria analysis, the m-factors for the Life Safety performance level in cyclic tests ranged from 1.6 to 1.8 for surface spline connections and from 0.9 to 1.7 for cyclic half-lap connections. The half-lap connections, where screws were installed in withdrawal, shear, shear, and withdrawal, performed exceptionally well with both high, linear-elastic, initial stiffness, and ductile, post-peak behavior.