A new timber frame structural system consisting of continuous columns, prefabricated hollow box timber decks and beam-to-column moment-resisting connections is investigated. The hollow box timber decks allow long spans with competitive floor height and efficient material consumption. To achieve long spans, semi-rigid connections at the corners of deck elements are used to join the columns to the deck elements. In the present paper, experimental investigations of a semi-rigid moment-resisting connection and a mock-up frame assembly are presented. The semi-rigid connection consists of inclined screwed-in threaded rods and steel coupling parts, connected with friction bolts. Full-scale moment-resisting timber connections were tested under monotonic and cyclic loading to quantify rotational stiffness, energy dissipation and moment resistance. The mock-up frame assembly was tested under cyclic lateral loading and with experimental modal analysis. The lateral stiffness, energy dissipation, rotational stiffness of the connections and the eigen frequencies of the mock-up frame assembly were quantified based on the experimental tests in combination with a Finite Element model, i.e., the model was validated with experimental results from the rotational stiffness tests of the beam-to-column connections. Finally, the structural damping measured with experimental modal analysis was evaluated and compared with FE model using the material damping of timber parts and equivalent viscous damping of the moment-resisting connections.