Cross-laminated timber (CLT) is a relatively new heavy timber construction material (also referred to as massive timber) that originated in central Europe and quickly spread to building applications around the world over the past two decades. Using dimension lumber (typically in the range of 1× or 2× sizes) glue laminated with each lamination layer oriented at 90° to the adjacent layer, CLT panels can be manufactured into virtually any size (with one dimension limited by the width of the press), precut and pregrooved into desirable shapes, and then shipped to the construction site for quick installation. Panelized CLT buildings are robust in resisting gravity load (compared to light-frame wood buildings) because CLT walls are effectively like solid wood pieces in load bearing. The design of CLT for gravity is relatively straightforward for residential and light commercial applications where there are plenty of wall lines in the floor plan. However, the behavior of panelized CLT systems under lateral load is not well understood especially when there is high seismic demand. Compared to light-frame wood shear walls, it is relatively difficult for panelized CLT shear walls to achieve similar levels of lateral deflection without paying special attention to design details, i.e., connections. A design lacking ductility or energy dissipating mechanism will result in high acceleration amplifications and excessive global overturning demands for multistory buildings, and even more so for tall wood buildings. Although a number of studies have been conducted on CLT shear walls and building assemblies since the 1990s, the wood design community’s understanding of the seismic behavior of panelized CLT systems is still in the learning phase, hence the impetus for this article and the tall CLT building workshop, which will be introduced herein. For example, there has been a recent trend in engineering to improve resiliency, which seeks to design a building system such that it can be restored to normal functionality sooner after an earthquake than previously possible, i.e., it is a resilient system. While various resilient lateral system concepts have been explored for concrete and steel construction, this concept has not yet been realized for multistory CLT systems. This forum article presents a review of past research developments on CLT as a lateral force-resisting system, the current trend toward design and construction of tall buildings with CLT worldwide, and attempts to summarize the societal needs and challenges in developing resilient CLT construction in regions of high seismicity in the United States.