This Chapter focuses on a few fastening systems that reflect present-day practices, some being conventional, while others are proprietary. Given the recent introduction of CLT into the construction market, it is expected that new connection types will be developed over time. Issues associated with connection design specific to CLT assemblies are presented. The European design approach is also presented and the applicability of the National Design Specification (NDS) for Wood Construction design provisions for traditional fasteners in CLT such as bolts, dowels, nails, and wood screws are reviewed and design guidelines are provided. Several design examples are also given at the end to demonstrate how connections in CLT can be established using current NDS design provisions.