Although not yet seen as common practice, building with cross laminated timber (CLT) is gaining momentum in North America. Behind the scenes of the widely publicized project initiatives such as the Wood Innovation Design Centre Building in Canada and the recent U.S. Tall Wood Building Competition, substantial research, engineering, and development has been completed or is underway to enable the adoption of this innovative building system. This paper presents a brief overview of the current status of CLT building development in North America, highlighting some recent U.S. and Canadian research efforts related to CLT system performance, and identifies future CLT research directions based on the needs of the North American market. The majority of the research summarized herein is from a recent CLT research workshop in Madison, Wisconsin, USA, organized by the USDA Forest Products Laboratory. The opportunity and need for coordination in CLT research and development among the global timber engineering community are also highlighted in the conclusions of this paper.