This paper describes the lateral force resisting system (LFRS) design in a full-scale six-story shake-table test building and presents a comparative cradle-to-grave life-cycle assessment of alternative LFRSs. The test building features the reuse of material from a ten-story shake-table structure comprised of engineered mass timber (MT) products. These include MT floors (cross-, glue-, nail-, and dowel-laminated timber [CLT], [GLT], [NLT], [DLT]); MT post tensioned rocking walls (CLT and mass ply panels [MPP]); and a gravity system consisting of laminated-veneer lumber (LVL) beams and columns. Shake-table testing will benchmark innovative, low-damage design solutions for the LFRSs. To supplement this test, the environmental impact of a MT LFRS is determined relative to design alternatives that use conventional materials. The Athena Impact Estimator for Buildings was used to perform a comparative, cradle-to-grave life-cycle assessment (LCA) of the prototype MT LFRS with respect to an alternative, functionally equivalent reinforced concrete (RC) shear wall design. The LCA results showed reduced environmental impacts across some impact metrics, with a significant reduction in Global Warming Potential for the MT LFRS when accounting for biogenic carbon.