In this work, the results from quasi-static cyclic tests on a novel hybrid steel-grout shear connector for cross-laminated timber (CLT) panels is presented. These tests are part of a set of experimental, analytical, and numerical studies aiming at developing a reliable and resilient hold-down connection for CLT panels in mass-timber construction. The cyclic tests have been done based on monotonic-test results, and all cyclic loading was done below the yield point of each connector. From cyclic-test results, mechanical characteristics, namely, the secant loading stiffness and the residual slip were evaluated and are discussed in the paper. Futhermore, analyses using Gaussian process regression machine learning algorithm were conducted in order to predict the mechanical characteristics of connectors in function of a vast number of inputs, including geometrical properties of connectors, mechanical properties of each material used, and physical parameters such as the position of lumber laminates in the CLT. It was shown that the steel rod diameter, the grout diameter, and the curing time of the grout are the most influencing parameters regarding the secant loading sitffness of connectors. As for the residual slip, it was found that the grout diameter, the steel rod grade, and the position of face-laminate joints in the CLT are the most influencing parameters. In overall, the results of this work contribute to an improved understanding of the connection under development and confirms the resilience of individual connectors under cyclic loads.