The dynamic response of semi-rigid timber frames subjected to wind loads is investigated numerically in this paper. The dynamic response of more than one million unique frames with different parameters was assessed with the frequency-domain gust factor approach, which is currently adopted by Eurocode 1, and the time-domain generalized wind load method. In the generalized wind load method, the frames were simulated for three different wind velocities with five simulations per unique combination of parameters, resulting in more than twelve million simulations in total. Qualitative and quantitative observations of the dataset were made. Empirical expressions for the accelerations, displacements, and fundamental eigenfrequency were proposed by the use of nonlinear regression applied to the obtained numerical results and a frequency reduction factor was developed. The wind-induced accelerations obtained by the two methods were compared to the corresponding serviceability criteria according to ISO10137, providing insight about the feasibility of moment-resisting frames as a lateral load-carrying system for mid-rise timber buildings. Comparison between the theoretical gust factor approach and the generalized wind load method showed that the gust factor approach was nonconservative in most cases. Finally, the effect of uniform and non-uniform mass distributions was investigated, with a theoretical reduction in top-floor accelerations of 50% and 25% respectively.