Cross-laminated timber (CLT) panels are broadly utilized as structural members in modern timber structures. Variation in the residual resistance of CLT walls after fire exposure may lead to disruption of vertical force transmission and, in turn, structural collapse. To investigate the residual compressive load-carrying capacity of CLT walls after exposed to one-side fire, a series of tests were conducted on 3-ply and 5-ply members: axial compression tests, fire tests, and residual compressive load-carrying capacity tests. Combining the initial geometric defects obtained from the test results and the effect of shear deformation, theoretical formulae describing the compressive load-carrying capacity were deduced. Further considering the different mechanical properties over the residual cross-section model after fire, and the relative position between Region A and CLT orthogonal configuration, the calculation method of the residual compressive load-carrying capacity after fire were derived. The results of the residual compressive load-carrying capacity tests showed that the failure mode of the CLT walls after one-side fire was the eccentric compression, and the nonlinear segments of the load-axial and load-lateral displacement curves after fire accounted for larger proportion than those of axial compression tests. For the same total section thickness, the reduction in residual capacity of the 5-ply walls after fire was less than that of the 3-ply walls. The calculation results of the eccentric compression formulae considering shear deformation and initial geometric defect showed good agreement with the test values of axial compression tests. The residual compressive load-carrying capacity after one-side fire was predicted appropriately, which could be used as reference for assessing the residual load-carrying behavior of CLT elements after fire.