Cross laminated timber (CLT) is a wood panelling building system that is used in construction, e.g. for floors, walls and beams. Because of the increased use of CLT, it is important to have accurate simulation models. CLT systems are simulated with one-dimensional and two-dimensional (2D) methods because they are fast and deliver practical results. However, because non-edge-glued panels cannot be modelled under 2D, these results may differ from more accurate calculations in three dimensions (3D). In this investigation, CLT panels with different width-to-thickness ratios for the boards have been simulated using the finite element method. The size of the CLT-panels was 3.0 m × 3.9 m and they had three and five laminate layers oriented 0°–90°–0° and 0°–90°–0°–90°–0°. The thicknesses of the boards were 33.33, 40.0, and 46.5 mm. The CLT panel deformation was compared by using a distributed out-of-plane load. Results showed that panels with narrow boards were less stiff than wide boards for the four-sided support setup. The results also showed that 2D models underestimate the displacement when compared to 3D models. By adjusting the stiffness factor k88, the 2D model displacement became more comparable to the 3D model.