European experience shows that besides single family housing, Cross-Laminated Timber (CLT) can be competitive in mid-rise and high-rise buildings. Although this system has not been used to the same extent so far in North America, it can be viable wood structural solution for the shift towards sustainable densification of urban and suburban centres. FPInnovations has undertaken a multidisciplinary project on determining the structural properties of a typical CLT construction, including quantifying the seismic resistance and force modification factors of CLT buildings. In this paper, some of the results from a series of quasi-static tests on CLT wall panels are presented as well as preliminary estimates for the force modification factors (R-factors) for seismic design of CLT structures. CLT wall panels with various configurations and connection details were tested. Wall configurations included single panels without openings with three different aspect ratios, panels with openings, as well as multi-panel walls with step joints and fasteners between them. Connections for securing the walls to the foundation included off-the-shelf steel brackets with annular ring nails, spiral nails, and screws; a combination of steel brackets and hold-downs; and custom made brackets with timber rivets. Results from two storey configurations that include two walls and a CLT slab in between are presented and discussed. Finally preliminary estimates and recommendations for the force modification factors (R-factors) for seismic design of CLT structures according to National Building Code of Canada (NBCC) are also made.