Structural possibility of CLT (Cross Laminated Timber) buildings in Japan is supposed to be smaller than that in other countries because of high seismic risk. In this paper, dealing 2 kind of middle-rise CLT panel construction method as objectives, the required wall quantity from the structural design method ruled in the building standard low of Japan is examined based on the knowledge from the national research project carrying out by the subsidy of MLIT (Ministry of Land, Infrastructure, Transport and Tourism) of Japan since 2011, and on the Japanese government notifications on structural design of CLT buildings issued on Apr. 1, 2016. As result, the required wall quantity in construction methods using rectangular narrow panel is generally regarded as practicable. However, reduction of wall quantity is expected for prevalence of CLT buildings. On the other hand, in construction methods using large rectangular panels with opening(s), the required wall quantity is confirmed generally 1.6 times larger than the former indicating poor practicability