This paper aims to discuss timber-wood lightweight concrete composites for application in wall components for buildings. The aim is to develop a multi-layer wall system composed of wood lightweight concrete, connected timber sections to gain and use advantages of each used material – lightweight, structural, thermal storage and insulation, ecological and economic benefits – to name the most important ones. The development of timber-wood lightweight concrete composites systems will lead to a new generation of polyvalent multi-material building components. By using renewable resources, waste products of the forest industry, and manufactured wood products, this technology provides statically and energy-efficient components for low-energy constructions. Such products support rapid-assembly construction methods, which use prefabricated dry elements to increase the efficiency of the construction. Wood-based alternatives to conventional concrete or masonry construction also open opportunities to reduce the carbon emissions.