This paper deals with the conception and characterization of an innovative connection for cross-laminated timber (CLT) panels. The connection is designed to provide an adequate level of dissipative capacity to CLT structures also when realized with large horizontal panels and therefore prone to fragile shear sliding failure. The connector, named X-bracket, has been theorized and designed by means of numerical parametric analyses. Furthermore, its cyclic behavior has been verified with experimental tests and compared to that of traditional connectors. Numerical simulations of cyclic tests of different CLT walls anchored to the foundation with X-brackets were also performed to assess their improved seismic performances. Finally, the analysis of the response of a 6 m × 3 m squat wall demonstrates that the developed connection provides good ductility and dissipation capacities also to shear walls realized with a single CLT panel.